Search results for "Urological Agents"

showing 4 items of 4 documents

Highly Selective Detection of Nerve‐Agent Simulants with BODIPY Dyes

2014

Two chromo-fluorogenic probes, each based on the boron dipyrromethene core, have been developed for the detection of nerve-agent mimics. These chemosensors display both a color change and a significant enhancement of fluorescence in the presence of diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP). No interference from other organophosphorus compounds or acids has been observed. Two portable chemosensor kits have been developed and tested to demonstrate its practical application in real-time monitoring.

Analytical chemistrysensorsCatalysischemistry.chemical_compoundQUIMICA ORGANICAfluorescent probesmedicinePhosphorylationColoring AgentsBoronFluorescent DyesNerve agentNeurological agentsMolecular StructurephosphorylationChemistryQUIMICA INORGANICAOrganic ChemistryGeneral ChemistryHighly selectiveCombinatorial chemistryFluorescenceBODIPYboronmedicine.drugChemistry – A European Journal
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Therapeutic Modulation of Urinary Bladder Function: Multiple Targets at Multiple Levels

2015

Storage dysfunction of the urinary bladder, specifically overactive bladder syndrome, is a condition that occurs frequently in the general population. Historically, pathophysiological and treatment concepts related to overactive bladder have focused on smooth muscle cells. Although these are the central effector, numerous anatomic structures are involved in their regulation, including the urothelium, afferent and efferent nerves, and the central nervous system. Each of these structures involves receptors for—and the urothelium itself also releases—many mediators. Moreover, hypoperfusion, hypertrophy, and fibrosis can affect bladder function. Established treatments such as muscarinic antago…

Central Nervous Systemmedicine.medical_specialtyUrinary BladderPopulationCentral nervous systemMuscarinic Antagonistsurologic and male genital diseasesToxicologyBioinformaticsMuscle hypertrophyNeurons EfferentFibrosisInternal medicinemedicineAnimalsHumansNeurons AfferentUrotheliumeducationPharmacologyeducation.field_of_studyUrinary bladderbusiness.industryUrinary Bladder DiseasesMuscle SmoothAdrenergic beta-AgonistsHyperplasiamedicine.diseasefemale genital diseases and pregnancy complicationsUrodynamicsTreatment OutcomeEndocrinologymedicine.anatomical_structureOveractive bladderAdrenergic alpha-1 Receptor AntagonistsUrological AgentsUrotheliumbusinessSignal TransductionAnnual Review of Pharmacology and Toxicology
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Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between…

2014

serenoa repensMaleProstatic HyperplasiaAntioxidantsSettore MED/24 - UrologiaSeleniumDouble-Blind MethodDrug TherapyLower Urinary Tract SymptomsSerenoa80 and overHumansBPH; LUTS; lycopene; phytotherapy; selenium; serenoa repens; tamsulosin; Aged; Aged 80 and over; Antioxidants; Carotenoids; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Lower Urinary Tract Symptoms; Male; Middle Aged; Phytotherapy; Prostatic Hyperplasia; Quality of Life; Selenium; Serenoa; Sulfonamides; Treatment Outcome; Urodynamics; Urological AgentsAgedSulfonamidesLUTSphytotherapyMiddle AgedlycopeneCarotenoidsBPH LUTS lycopene phytotherapy selenium serenoa repens tamsulosinUrodynamicsTreatment OutcomeItalyBPHtamsulosinCombinationQuality of LifeUrological Agentsserenoa repens; lycopene; selenium; tamsulosin; LUTS; BPH; phytotherapy
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EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction.

2013

To present a summary of the 2013 version of the European Association of Urology guidelines on the treatment and follow-up of male lower urinary tract symptoms (LUTS). We conducted a literature search in computer databases for relevant articles published between 1966 and 31 October 2012. The Oxford classification system (2001) was used to determine the level of evidence for each article and to assign the grade of recommendation for each treatment modality. Men with mild symptoms are suitable for watchful waiting. All men with bothersome LUTS should be offered lifestyle advice prior to or concurrent with any treatment. Men with bothersome moderate-to-severe LUTS quickly benefit from α1-blocke…

Malemedicine.medical_specialtyPhosphodiesterase Inhibitorsmedicine.medical_treatmentUrologyUrologyProstatic HyperplasiaMuscarinic AntagonistsSeverity of Illness Indexchemistry.chemical_compound5-alpha Reductase InhibitorsLower Urinary Tract SymptomsLower urinary tract symptomsmedicineNocturiaHumansWatchful WaitingTransurethral resection of the prostateUrinary retentionProstatectomybusiness.industryTransurethral Resection of Prostatemedicine.diseaseDutasterideTreatment OutcomechemistryAdrenergic alpha-1 Receptor AntagonistsUrological AgentsProstate surgeryStentsmedicine.symptombusinessUrinary CatheterizationRisk Reduction BehaviorWatchful waitingEuropean urology
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